Pain-killer warning for heart patients

Heart patients should not be given many common pain-killers, researchers warned last night.

Drugs such as ibuprofen are strongly linked to an increased risk of heart patients having a new heart attack, Danish researchers found.

Experts said the findings went beyond current advice that the drugs – non-steroidal anti-inflammatory drugs – should be used "with caution" on heart patients.

The Danish researchers found that taking the drugs increased the risk of having a heart attack by nearly half.

Anne-Marie Schjerning Olsen, of Copenhagen University Hospital, studied some 83,000 patients – who suffered more than 35,000 heart attacks or deaths between them.

Writing in Circulation, she says the common drug, diclofenac, poses the greatest risk – increasing the risk of illness or death by more than three times.

Dr Mike Knapton, of the British Heart Foundation, said: “We have known for some time that non-steroidal anti-inflammatory drugs should be used with caution in patients with heart disease.

"This study suggests that even short-term use appears to carry a significant risk in patients who’ve had a heart attack.

"In practice this study emphasises the need for extremely careful use of these painkillers in people who’ve had a heart attack. If you are in pain there are effective alternatives, such a paracetamol or codeine. But you should always talk this through with your doctor to weigh up the pros and cons of all medication options."

Duration of Treatment With Nonsteroidal Anti-Inflammatory Drugs and Impact on Risk of Death and Recurrent Myocardial Infarction in Patients With Prior Myocardial Infarction. Anne-Marie Schjerning Olsen et al. Circulation May 9 2011.DOI: 10.1161/CIRCULATIONAHA.110.004671

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