British researchers say they have made a key step in the battle against the ageing of the human body.
The Leicester University researchers are developing technology to identify “old cells”, which contribute to symptoms of ageing when they accumulate.
The researchers say their findings may also help in detection of cancer.
The scientists say they have found new chemical markers that indicate the presence of old cells.
They have reported their findings in Cell Death and Disease.
Researcher Dr Salvador Macip said: “What we have found is a series of novel markers – a way to detect senescent cells. What is more, we have shown that they can be used to predict increased survival in certain types of cancer.
“Until now, good protocols to help spot these cells have been sadly lacking. Our research has described new markers located on the surface of the old cells.”
He added: “These markers could be useful tools not only to study senescent cells in the lab but also they could be developed into diagnostics to help predict survival in cancer patients.
“Moreover, they could also be used in the future to define strategies to selectively eliminate the old cells from the tissues and thus reduce their effects on promoting ageing in healthy subjects.”
Cell Death and Disease 9 December 2014 [abstract]
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