SIGN UP FOR UPDATES!
Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
ENGLEMED
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BOOKS AND GIFTS THIS WAY!
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
SEARCH THIS SITE
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
FreeDigitalPhotos
www.freedigitalphotos.net
FreeWebPhotos
www.freewebphoto.com
FROM OUR NEWS FEEDS
SARS-CoV-2 mutations 'do not increase transmissibility'
Thurs November 26th - None of the SARS-CoV-2 virus mutations that have been documented so far increase transmissibility in humans, a new study has shown. More
Midlife high blood pressure linked to elderly brain damage
Thurs November 26th - High blood pressure in middle age is associated with the development of more extensive brain damage when elderly, researchers report today. More
Activity can offset sedentary lifestyle - WHO says
Thurs November 26th - Exceeding the recommendations for weekly physical activity can offset the health harms associated with prolonged sitting, says new guidelines from the World Health Organisation. More
RECENT COMMENTS
On 09/10/2020 William Haworth wrote:
How long is recovery time after proceedure... on Ablation cuts atrial fibrillat...
On 04/08/2020 VICKY P ADAM wrote:
I would like to thank WORLD HERBS CLINIC for reve... on Medieval remedy for bacterial ...
On 29/07/2020 Amdre wrote:
When i read many blogs online about cure to HSV, a... on Medieval remedy for bacterial ...
On 14/07/2020 margret wrote:
I was diagnosed of ALS (amyotrophic lateral sclero... on Heart abnormalities revealed i...
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
OUR CLIENTS
THIS WEEK'S STORIES
ENGLEMED HEALTH NEWS

COVID-19 antibody therapy candidates identified

Thursday October 29th 2020

UK scientists have identified a potentially ground-breaking antibody combination that could be used as a “cocktail” against COVID-19, it is revealed today.

The UK BIA Antibody Taskforce, a UK consortium that is developing antibodies to treat the virus, has created a pool of more than 600 novel candidates, identifying a set of antibodies with the greatest potential.

Dr Jane Osbourn, CSO at Alchemab and leader of the Taskforce, said they believe the most effective tool against COVID-19 is likely to be a defined mixture of two to three antibodies.

“We have accelerated the standard timelines for antibody discovery, taking seven months rather than the industry standard 18 months, establishing a pathway that can be applied to future pandemics,” she said, adding that the effectiveness of different combinations will have to be assessed.”

The candidate antibodies are the first to be selected for the next stage of development, following assessment by collaborators for potency.

Although work is ongoing to establish the cocktail’s efficacy, early indications show a potential competitively potent cocktail that is differentiated from other products that are under investigation in clinic.

It means the novel therapy candidates will move into the next phase of development, with further screening and safety testing.

Steve Bates, CEO of the BIA, said: “This ground-breaking Taskforce has brought together UK-based industry experts who share a joint commitment to help fight the COVID-19 pandemic.

“Contributing their expertise and specialist resources, the team has worked tirelessly to identify the most promising antibodies with the potential to positively impact treatment of those affected by this devastating virus. The next stage will involve securing external funding to facilitate the further development and manufacture of the candidates.”

The next phase will see the selected antibody cocktails being manufactured to support initial clinical trials in 2021.

* A study in New York City, USA, has reported that antibody responses can persist for five months in patients with mild to moderate disease, according to a report in Science yesterday.

The research involved 30,000 patients initially and then centred on 121 plasma donors, who had stable antibody levels for five months. The researchers say the antibodies appear to target a different viral antigen to that identified in other studies which have suggested that antibodies fade quite rapidly.

* Analysts GlobalData say hyperimmune intravenous immunoglobin already represents a “tantalising” treatment option, which is under investigation by the US National Institutes of Health. It creates a concentrated mixture of polyclonal antibodies.

* University College London is to lead a trial into two antiviral drugs, favipiravir and lopinavir/ritonavir, to test their effectiveness in early stages of infection.

Robust neutralizing antibodies to SARS-CoV-2 infection persist for months. Science 28 October 2020

https://science.sciencemag.org/cgi/doi/10.1126/science.abd7728

Tags: Flu & Viruses | North America | Pharmaceuticals | UK News

Printer friendly page Printer friendly page

Comment on this article:

Name:
Email:
Comment:
<a>,<b> & <p> tags allowed
Please enter the letters displayed:
(not case sensitive)
CATEGORIES