SIGN UP FOR UPDATES!
Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
ENGLEMED
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BOOKS AND GIFTS THIS WAY!
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
SEARCH THIS SITE
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
FreeDigitalPhotos
www.freedigitalphotos.net
FreeWebPhotos
www.freewebphoto.com
FROM OUR NEWS FEEDS
How virus affected breast screening Europe-wide
Thurs October 1st - The pressure on breast screening programmes across many European countries during the COVID-19 pandemic could lead to an increase in deaths from cancer, a conference will hear today. More
Care homes to test anti-inflammatory virus treatment
Thurs October 1st - An anti-tumour necrosis factor drug is to be tested as a community treatment for COVID-19 infection, it has been announced. More
RECENT COMMENTS
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote:
https://epidemicj17.imascientist.org.uk/2017/06/21... on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...
On 12/03/2017 Steph wrote:
The photo you have paired with this article is its... on 'Fat shaming' limits...
OUR CLIENTS
THIS WEEK'S STORIES
ENGLEMED HEALTH NEWS

Study to look at Covid-19 impact on blood cancer patients

Friday May 22nd, 2020

A new UK study is to be launched that will examine how patients who receive stem cell transplants for blood cancers and blood disorders react to severe Covid-19 infection.

Launched by IMPACT, a partnership of organisations that are jointly funded by Anthony Nolan, Leukaemia UK and NHS Blood and Transplant, the study will be led by Dr Giovanna Lucchini from Great Ormond Street Hospital.

It will monitor how adult and paediatric stem cell transplant recipients react to severe Covid-19 infection by profiling how their immune systems respond, and will also use clinical and biological characteristics to assess how the virus impacts their recovery and overall survival.

Once researchers have a better understanding of how these high-risk patients react to the new novel coronavirus, it could provide the scientific basis for using targeted therapy with biological agents to treat them more effectively.

Current data suggests that 15% of people infected with Covid-19 will have to receive hospital treatment, including respiratory support.

However, patients taking medication for conditions like graft vs host disease (GvHD), could also suffer from additional complications that could lead to patients taking longer to recover.

IMPACT Medical Director Professor David Marks said the study aims to recruit between 20 and 60 stem cell transplant patients being treated in IMPACT centres across the UK.

To be eligible, patients must have tested positive for Covid-19 and have symptoms that require oxygen treatment.

Researchers will need to take a blood sample within 72 hours of the patient receiving oxygen to enable analysis for immunological biomarkers, including white blood cell numbers and signalling molecules that control the immune system.

Patients will be examined at 30 and 100 days following their Covid-19 diagnosis to assess their recovery progress.

Prof Marks said: “This non-interventional study will recruit adults and children from UK IMPACT centres and may help us better understand the mechanisms of lung dysfunction in this patient group, and the factors that are associated with an adverse outcome.

“Transplant patients who are infected may react differently to the normal population; there is already some evidence that this infection is very serious after a transplant. Understanding the changes in cytokines may enable us to offer these patients targeted therapies with the goal of improving outcomes.”

Anthony Nolan’s chief executive Henny Braund said: “This important study has the potential to offer a promising step forward in how we understand the effects of the Covid-19 respiratory illness on patients with weakened immune systems.”

NHS Blood and Transplant’s James Griffin, consultant haematologist at NHS Blood and Transplant and University Hospitals Bristol added: “IMPACT has enabled the trial to be set up and opened in an incredibly short time and should result in quick recruitment. This is novel research led by an expert team at Great Ormond Street Hospital and will provide important data to help inform stem cell transplant doctors and patients during the current SARS-CoV2 pandemic.”

Source: Anthony Nolan

Tags: Cancer | Flu & Viruses | Respiratory | UK News

Printer friendly page Printer friendly page

Comment on this article:

Name:
Email:
Comment:
<a>,<b> & <p> tags allowed
Please enter the letters displayed:
(not case sensitive)
CATEGORIES