Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
Warning on growing palliative care needs
Thurs May 23rd - The number of people needing palliative care globally is set to double in the next 40 years, according to a new projection. More
Red wine compound investigated for hypertension care
Thurs May 23rd - A compound produced by fruits in response to injury or attack could hold the key for to new treatments for hypertension, researchers report today. More
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote: on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...
On 12/03/2017 Steph wrote:
The photo you have paired with this article is its... on 'Fat shaming' limits...

Green tea molecule could prevent heart attacks

Friday June 1st, 2018

A compound in green tea could be used to help prevent deaths from heart attacks and strokes caused by atherosclerosis, researchers reported today.

Researchers from Lancaster University and the University of Leeds, England, found that epigallocatechin-3-gallate (EGCG), which is most commonly associated with green tea, breaks up and dissolves potentially dangerous protein plaques found in the blood vessels.

In advanced stages of atherosclerosis, apolipoprotein A-1 (apoA-1) can form amyloid deposits, which are similar in structure to those associated with Alzheimer’s disease. Those deposits build up within atherosclerotic plaques, increase the size of the plaques, which further restrict blood flow. This increases the risk of a heart attack or stroke.

However, writing in the Journal of Biological Chemistry, the team says that EGCG binds to the amyloid fibres of apoA-1, which converts the fibres to smaller soluble molecules that are less likely to be damaging to blood vessels.

David Middleton, professor in Chemistry at Lancaster University, said: “The health benefits of green tea have been widely promoted and it has been known for some time that EGCG can alter the structures of amyloid plaques associated with Alzheimer’s disease. Our results show that this intriguing compound might also be effective against the types of plaques which can cause heart attacks and strokes.”

Professor Sheena Radford, director of the Astbury Centre for Structural Molecular Biology at the University of Leeds and co-author of the study, said: “The findings of this round of studies are very encouraging. We now need to apply the best scientific techniques to find how we can take the molecular EGCG element from green tea, and turn it into a functioning tool to combat life-limiting health issues.”

Professor Jeremy Pearson, associate medical director at the British Heart Foundation, which funded the study said although swapping black tea for green is unlikely to make a big difference with respect to heart health, engineering the molecule slightly could lead to new medicines to treat heart attack and stroke.

The team is now looking into how large amounts of EGCG could be introduced into the bloodstream without the need to drink large – and potentially harmful – quantities of green tea.

Journal of Biological Chemistry 1 June 2018

Tags: Diet & Food | Heart Health | UK News

Printer friendly page Printer friendly page

Comment on this article:

<a>,<b> & <p> tags allowed
Please enter the letters displayed:
(not case sensitive)