SIGN UP FOR UPDATES!
Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
ENGLEMED
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BOOKS AND GIFTS THIS WAY!
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
SEARCH THIS SITE
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
FreeDigitalPhotos
www.freedigitalphotos.net
FreeWebPhotos
www.freewebphoto.com
FROM OUR NEWS FEEDS
Heatwave horsefly risk warning
Fri July 13th - High levels of horseflies amid the human population could test the limits of antibiotics, campaigners warn today. More
RECENT COMMENTS
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote:
https://epidemicj17.imascientist.org.uk/2017/06/21... on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...
On 12/03/2017 Steph wrote:
The photo you have paired with this article is its... on 'Fat shaming' limits...
BOOKS ON CHILDREN'S HEALTH
Child health, sickness and symptoms guide Child health guide
For more books, child safety and gift ideas click here
NEWS FEEDS
ENGLEMED HEALTH NEWS

High-dose chemo for neuroblastoma

Wednesday July 11th, 2018

A new study has looked at long-term outcomes for children with high-risk neuroblastoma treated with high-dose chemotherapy plus autologous stem cell transplantation.

Professor Frank Berthold of University Hospital Cologne, Germany, and colleagues analysed the outcomes of patients in the NB97 trial after over 13 years of follow-up.

Results showed that this approach was more effective than maintenance chemotherapy in terms of cancer recurrence for all patient subgroups. Long-term overall survival was also better in the high-dose chemotherapy group.

Long-term chemotherapy side-effects included auditory impairment, thyroid dysfunction, and renal function impairment. But the researchers believe these were mainly due to the initial chemotherapy given at first diagnosis.

Their findings are published today (11 July) in The British Journal of Cancer.

The experts write: "High-risk neuroblastoma represents still one of the leading causes for death from childhood cancer. Even after good initial responses to chemotherapy, many tumour recurrences are observed suggesting the need for an effective consolidation therapy."

In a separate recent study, Professor Berthold and colleagues report that the ten-year overall survival for neuroblastoma patients, between 1979 and 2015, increased for stage 1-3 neuroblastoma from 83% to 91%, for stage 4S from 80% to 85%, and for stage 4 from 2% to 38%.

They state that 97% of known neuroblastoma patients in Germany took part in a clinical trial, and add that the neuroblastoma rate has increased slightly, while the median age at diagnosis has fallen.

The rate of patients in stages 1-3 who are not given chemotherapy increased during this time from 35% to 60%.

Berthold, F. et al. The British Journal of Cancer 11 July 2018; doi: s41416-018-0169-8

https://www.nature.com/articles/s41416-018-0169-8

Tags: Brain & Neurology | Cancer | Child Health | Europe | Pharmaceuticals | UK News

Printer friendly page Printer friendly page

Comment on this article:

Name:
Email:
Comment:
<a>,<b> & <p> tags allowed
Please enter the letters displayed:
(not case sensitive)
CATEGORIES