Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
Sex differences in cardiovascular disease risk
Wed January 27th - Doctors often mistake the development of hypertension in women for symptoms of menopause, according to a new analysis. More
Hope for end to melanoma rates growth
Wed January 27th - The growth in melanoma incidence in young adults has “stabilised” this century, suggesting that public health messages may have had some success, according to a new UK study. More
On 09/10/2020 William Haworth wrote:
How long is recovery time after proceedure... on Ablation cuts atrial fibrillat...
On 04/08/2020 VICKY P ADAM wrote:
I would like to thank WORLD HERBS CLINIC for reve... on Medieval remedy for bacterial ...
On 29/07/2020 Amdre wrote:
When i read many blogs online about cure to HSV, a... on Medieval remedy for bacterial ...
On 14/07/2020 margret wrote:
I was diagnosed of ALS (amyotrophic lateral sclero... on Heart abnormalities revealed i...
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...

Chemo ear protection plan

Thursday September 14th, 2017

A new research project is underway to help avoid hearing loss caused by the chemotherapeutic drug cisplatin, often used to treat childhood cancers.

The US-based research company Otomagnetics is carrying out the project with funding from the UK charity Action on Hearing Loss.

Dr Ralph Holme of Action on Hearing Loss explains that although steroids can limit the amount of hearing loss caused by cisplatin, the current method of delivering steroids to the cochlea - injecting liquid steroids through the ear drum into the middle ear - is inefficient. The drug needs to be directly delivered to the cochlea otherwise it can reduce the impact of chemotherapy.

The new project aims develop a new method for delivering steroids directly to the cochlea. It uses magnetic fields to insert drug-covered iron nanoparticles into the cochlea. In tests, this method is more effective, reducing hearing loss in mice treated with cisplatin by 50%.

Dr Holme said: "It is vital that we find effective ways of getting drugs into the inner ear, which is why we are backing Otomagnetics.

"It is great news that progress is being made towards finding new ways to protect children's hearing following cancer treatment with cisplatin which causes the sensory hair cells in the cochlea that detect sound to die and can leave cancer survivors who have already gone through a traumatic experience depressed and isolated."

He adds that the same technique could be used to deliver any drug or stem cell-based treatment to the ear, and to deliver drugs into eyes or into skin.

Ramaswamy, B. et al. Magnetic nanoparticle mediated steroid delivery mitigates cisplatin induced hearing loss. Frontiers in Cellular Neuroscience 13 September 2017; doi: 10.3389/fncel.2017.00268 [abstract]

Tags: Cancer | Child Health | Hearing | North America | Pharmaceuticals | UK News

Printer friendly page Printer friendly page

Comment on this article:

<a>,<b> & <p> tags allowed
Please enter the letters displayed:
(not case sensitive)