SIGN UP FOR UPDATES!
Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
ENGLEMED
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BOOKS AND GIFTS THIS WAY!
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
SEARCH THIS SITE
Google

WWW Englemed
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
FreeDigitalPhotos
www.freedigitalphotos.net
FreeWebPhotos
www.freewebphoto.com
FROM OUR NEWS FEEDS
Epithelial cell states distinguish between uterine cancers
Fri December 3rd - Two epithelial cell states have been identified that can help to distinguish between types of uterine cancer, British researchers announced last night. More
COVID-19 boosters increase immunity
Fri December 3rd - Six different types of COVID-19 boosters are safe and increase immunity following vaccination with either the AstraZeneca or Pfizer-BioNTech jabs, British researchers report today. More
RECENT COMMENTS
On 09/10/2020 William Haworth wrote:
How long is recovery time after proceedure... on Ablation cuts atrial fibrillat...
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote:
https://epidemicj17.imascientist.org.uk/2017/06/21... on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...
OUR CLIENTS
THIS WEEK'S STORIES
ENGLEMED HEALTH NEWS

Gene test may be needed for diabetes type 2

Wednesday September 13th, 2017

Genetic screening may be needed to identify people at raised risk of type 2 diabetes, researchers reported last night.

Many genetic variants significantly impact the results of the HbA1c blood test used to diagnose the condition, so a team from the Wellcome Trust Sanger Institute, Cambridge, UK, took a closer look.

Along with an international team of more than 200 scientists, the Cambridge team carried out the largest study of its kind. They studied genetic variants in almost 160,000 diabetes-free people from European, African, East Asian and South Asian ancestries, followed over time.

This highlighted 60 genetic variants that influence the outcome of HbA1c tests, of which 42 were new. One in particular was found to significantly impact the results of the HbA1c test - the G6PD genetic variant. It is almost unique to people of African ancestry, report the researchers, with about 11% of African Americans carrying at least one copy.

They reported in PLoS Medicine yesterday (12 September) that: "We found that the more glycaemic variants a person had, the higher their risk to get diabetes."

They add that variants which lower HbA1c levels independently from glucose concentration could lead to missed diagnosis of diabetes.

They conclude: "As a G6PD deficiency can be clinically silent until illness strikes, we recommend investigation of the possible benefits of screening for the G6PD genotype along with using HbA1c to diagnose type 2 diabetes in populations of African ancestry or groups where G6PD deficiency is common.

"Screening with direct glucose measurements, or genetically-informed HbA1c diagnostic thresholds in people with G6PD deficiency, may be required to avoid missed or delayed diagnoses."

* The NHS is due to get the go-ahead today to offer flash glucose monitoring, according to reports.

Diabetes UK said it would be “fantastic news,” sparing patients from finger-prick testing.

Wheeler, E. et al. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Medicine 12 September 2017; doi: 10.1371/journal.pmed.1002383 [abstract]

Tags: Africa | Diabetes | Genetics | UK News | World Health

Printer friendly page Printer friendly page

Comment on this article:

Name:
Email:
Comment:
<a>,<b> & <p> tags allowed
Please enter the letters displayed:
(not case sensitive)
CATEGORIES