Algae hope for diagnostic nanobots
Thursday November 23rd, 2017
Remote controlled nanobots could be engineered from algae to make them
biodegradeable and useful for medicine, researchers reported last night.
The nanobots were developed by Professor Li Zhang at the Chinese University
of Hong Kong, together with experts at Manchester University, UK, from
spirulina algae.
The algae are thought to have been a source of nourishment in central
America at the time of the Aztecs. They are biodegradable and available
for sale as a food substitute in health food shops.
The team investigated the compound's biodegradability to develop nanobots
that degrade at a predictable rate due to an iron magnetic coating. Thanks
to this feature, the nanorobots can be remotely controlled with high
precision using magnetic fields to target tumours and release anti-cancer
drugs.
Details appear on 22 November in Science Robotics.
Professor Kostas Kostarelos from Manchester University said: "Rather
than fabricate a functional microrobot from scratch using intricate laboratory
techniques and processes, we set out to directly engineer smart materials
in nature, which are endowed with favourable functionalities for medical
applications owing to their intrinsic chemical composition.
"For instance, because these biohybrid bots have a naturally fluorescent
biological interior and magnetic iron-oxide exterior, we can track and
actuate a swarm of those agents inside the body quite easily using fluorescence
imaging and magnetic resonance imaging."
He added that the microrobots can sense changes in environments associated
with the illness onset, and adds: "We must now develop this technology
further so we are able to fine tune this image-guided therapy and create
a proof of concept for the engineering of multifunctional microrobotic
and nanorobotic devices."
The team say they need to improve the nanobots' motion tracking, biocompatibility,
biodegradation, and diagnostic and therapeutic effects.
Zhang, L. et al. Multifunctional biohybrid magnetite
microrobots for imaging-guided therapy. Science
Robotics 22
November 2017; doi: 10.1126/scirobotics.aaq1155
Tags: Asia | General
Health | South America | UK
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