SIGN UP FOR UPDATES!
Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
ENGLEMED
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BOOKS AND GIFTS THIS WAY!
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
SEARCH THIS SITE
Google

WWW Englemed
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
FreeDigitalPhotos
www.freedigitalphotos.net
FreeWebPhotos
www.freewebphoto.com
FROM OUR NEWS FEEDS
Heart failure linked to heavy energy drink consumption
Fri April 16th - Drinking excessive energy drinks could be linked to a young man’s heart failure, according to doctors who treated a 21-year-old who consumed four cans a day for two years. More
Shift workers' heart health linked to body clock
Fri April 16th - The risk of heart disease becomes greater the more an individual works outside of their natural body clock, new research suggests. More
Infection much greater risk than vaccines for thrombotic events
Fri April 16th - Cerebral venous thrombosis has been a significant complication of COVID-19 at a rate far higher than seen after vaccination, British researchers have reported. More
RECENT COMMENTS
On 09/10/2020 William Haworth wrote:
How long is recovery time after proceedure... on Ablation cuts atrial fibrillat...
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote:
https://epidemicj17.imascientist.org.uk/2017/06/21... on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...
BOOKS ON CHILDREN'S HEALTH
For books, child safety and gift ideas click here
NEWS FEEDS
ENGLEMED HEALTH NEWS

Infections in babies ‘increase diabetes risk’

Friday May 6th, 2016

Babies who develop viral respiratory infections in their first six months face an increased risk of type 1 diabetes as they grow older, according to a German study.

A study conducted by scientists at the Helmholtz Zentrum München, Germany, say their findings provide a further piece in the puzzle in understanding how type 1 diabetes develops.

Before this study, there were only inconsistent indications from studies with children with a genetically higher risk of type 1 diabetes regarding the influence of infections.

However, the team examined anonymised data from almost 300,000 children born in Bavaria between 2005 and 2007, which represents about 85% of all new-borns in the region during those years.

They evaluated all available data on infections, breaking them down to localised symptoms, such as dermal, eye, gastrointestinal or respiratory infections, whether the cause was bacterial, viral or mycoses, and the babies’ ages.

Prof Dr Anette-Gabriele Ziegler, director of the Institute of Diabetes Research (IDF) at Helmholtz Zentrum München, who led the study, said: “Now for the first time we were able to confirm this in a population-based dataset of almost 300,000 children. In particular, we found strong indications that the first six months are an especially sensitive stage in life.

“This is also consistent with other results that we have published based on data from children with increased familial risk, which already suggested that the first half year of life is crucial for the development of the immune system and of autoimmune diseases such as type 1 diabetes.”

The research, which is published in JAMA, found that infections that occurred later or that involved other organs were not associated with a significantly higher risk.

* Researchers have quantified for the first time a patient’s risk of developing diabetes if they take a common steroid for rheumatoid arthritis (RA).

According to the University of Manchester team, the risk of developing diabetes when taking glucocorticoids, which is prescribed to about half of RA patients, increases in relation to the dosage, duration and timing of steroids.

The researchers reveal their findings after examining the records of 21,962 RA patients and looking at rates of new-onset diabetes, comparing those who were prescribed glucocorticoids and those who were not.

Writing in Arthritis and Rheumatology, they say that glucocorticoids were associated with one new case of diabetes for every 150-200 people treated per year.

Within this group, risk was affected by the dose only in the most recent six months, with each increase of 5mg prednisolone per day carrying a 25-30% increase in diabetes. Doses under 5mg were not associated with a measurable risk of diabetes.

The results were also checked against 12,657 USA-held records.

Lead author Dr Will Dixon, director of the Arthritis Research UK Centre for Epidemiology at The University of Manchester and Honorary Consultant Rheumatologist at Salford Royal NHS Foundation Trust, said: “Until now, no studies have considered how the risk changes with the dose and duration of treatment. This research provides important evidence for doctors to make this decision.”

He added: “This research shows that low doses of steroids (below 5mg/ day) do not increase the risk of diabetes. However, there is an increased risk of acquiring diabetes for people who use them for long periods or at high doses which can now be quantified.”

The research does not recommend that people stop using glucocorticoids.

Beyerlein, A. et al. (2016). Infections in early life and development of type 1 diabetes. JAMA. May 2016. doi: 10.1001/jama.2016.2181

Movahedi M, Beauchamp M-E, Abrahamowicz M et al. Risk of Incident Diabetes Associated with Dose and Duration of Oral Glucocorticoid Therapy in Patients with Rheumatoid Arthritis. Arthritis and Rheumatology. DOI: 10.1002/art.39537

Tags: Child Health | Diabetes | Europe | Flu & Viruses

Printer friendly page Printer friendly page

Comment on this article:

Name:
Email:
Comment:
<a>,<b> & <p> tags allowed
Please enter the letters displayed:
(not case sensitive)
CATEGORIES