SIGN UP FOR UPDATES!
Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
ENGLEMED
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BOOKS AND GIFTS THIS WAY!
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
SEARCH THIS SITE
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
FreeDigitalPhotos
www.freedigitalphotos.net
FreeWebPhotos
www.freewebphoto.com
FROM OUR NEWS FEEDS
Worldwide measles outbreak deadly for infants
Fri Dec 6th - The world has been facing a "devastating" outbreak of measles, leading to thousands of deaths, according to stark new figures. More
Bariatric surgery leads to heart improvements - conference
Fri Dec 6th - Obese individuals undergoing bariatric surgery could also reverse subclinical heart dysfunction, a conference has heard. More
RECENT COMMENTS
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote:
https://epidemicj17.imascientist.org.uk/2017/06/21... on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...
On 12/03/2017 Steph wrote:
The photo you have paired with this article is its... on 'Fat shaming' limits...
BOOKS ON CHILDREN'S HEALTH
For books, child safety and gift ideas click here
NEWS FEEDS
ENGLEMED HEALTH NEWS

Infant saved by genetically modified T cells - first treatment

Friday November 6th, 2015

An infant appears to have been cured of advanced leukaemia using an experimental treatment with genetically modified T-cells, it was announced yesterday.

The child, now aged 16 months, became the first patient to try the treatment, which was under development at Great Ormond Street Hospital, London, UK, and University College London.

Doctors gained special ethics permission to test the use of the UCART19 cells after all other treatment options ran out for the child.

The cells have been designed to be invisible to leukaemia drugs and to target leukaemia cells. Until now they have only been tested in laboratory mice.

The patient, Layla, was suffering from relapsed acute lymphoblastic leukaemia.

Layla had undergone chemotherapy, bone marrow transplants and another experimental treatment in Sheffield. Her family had been told that no further treatment existed.

Two weeks after a 1ml infusion of the UCART19 cells, Layla developed a rash, suggesting a working immune reaction.

After two months, Layla was free of cancer and received another bone marrow transplant.

Her father Ashleigh said: "Even though she is well at the moment, we still don’t know what the future holds. She will still have monthly bone marrow checks for now and might be on some medicines for the rest of her life."

Consultant immunologist Professor Waseem Qasim said: "We have only used this treatment on one very strong little girl, and we have to be cautious about claiming that this will be a suitable treatment option for all children.

"But, this is a landmark in the use of new gene engineering technology and the effects for this child have been staggering.

"If replicated, it could represent a huge step forward in treating leukaemia and other cancers."

Professor Paul Veys, the hospital's director of bone marrow transplant, added: "As this was the first time that the treatment had been used, we didn’t know if or when it would work and so we were over the moon when it did.

"Her leukaemia was so aggressive that such a response is almost a miracle."

Tags: Cancer | Child Health | Genetics | NHS | UK News

Printer friendly page Printer friendly page

Comment on this article:

Name:
Email:
Comment:
<a>,<b> & <p> tags allowed
Please enter the letters displayed:
(not case sensitive)
CATEGORIES