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Hope for Alzheimer's vaccine

Friday June 8th, 2012

An Alzheimer's disease vaccine is ready for large-scale testing, researchers have reported.

The vaccine has successfully been tested on 58 patients in Sweden, according to a report in Lancet Neurology.

Researchers at the Karolinska Institutet, Stockholm, say the vaccine CAD106 could prove a "breakthrough" in treatment of the disease.

The full effect of the vaccine on the disease is not yet known - but the researchers say the trial successfully showed that the vaccine can trigger the immune system to work against the disease.

The trial was the second to test the vaccine - but the researchers say it has been modified to ensure it only affects the beta-amyloid plaques which are thought to cause the disease.

The researchers say there were no significant side-effects linked to the vaccine. Patients were just as likely to report complications if they received a dummy injection as when they received the real vaccine.

Researcher Professor Bengt Winblad said the vaccine was a "tolerable" treatment for patients with mild to moderate disease.

Lancet Neurology, online first 6 June 2012, doi:10.1016/S1474-4422(12)70140-0

Tags: Brain & Neurology | Europe | Mental Health | Pharmaceuticals

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1At 21/06/2012 11:20pm Editor wrote

Teething troubles meant somebody posted a comment here that has been lost. Please repost and your comment will appear!

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