Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
SARS drug ready for clinical trial
Fri April 3rd - A drug developed to treat lung disease has shown early promise against the Covid-19 virus, researchers reported last night. More
'Promising' COVID-19 vaccine revealed
Fri April 3rd - A potential vaccine for COVID-19 has been described for the first time after promising mice studies, US scientists have revealed today (2 April 2020). More
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote: on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...
On 12/03/2017 Steph wrote:
The photo you have paired with this article is its... on 'Fat shaming' limits...
Clearing the air: An Assessment of Asthma and Indoor Allergens ABC of Asthma For more books click here
RSS graphic XML Graphic

Asthma inhaler targets small airways

Mon March 23rd, 2009

New research suggests that a popular asthma inhaler can effectively improve the function of "small airways".

Small airways play an important role in asthma, say experts, so treatments that go beyond the central airways and reach the small airways may be better for chronic asthma.

The experts tested the inhaled drug Symbicort (budesonide plus formoterol) on 1,076 asthma patients aged 12 years and older. Patients took either Symbicort, budesonide, formoterol, or inactive placebo for 12 weeks.

The researchers found that Symbicort "provided greater improvements in small airway function" than either of its components alone or placebo. It led to better lung function, as measured by forced expiratory flow, they explain.

In another study, patients used Symbicort or budesonide for a year. Those using Symbicort "experienced significantly greater improvements in forced expiratory flow" which were maintained for up to one year.

The results were presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting held in Washington, USA, on Monday (March 16).

Researcher Dr David Pearlman of Colorado Allergy and Asthma Centers, USA, said: "These studies are the first to evaluate and suggest an effect of Symbicort on mid-expiratory flow rates, one potential measure of small airway function.

"Small airways can be subject to inflammation and smooth muscle constriction, which are two main causes of asthma symptoms. Treatments that are able to reduce bronchial constriction and reduce inflammation in this area may be beneficial to patients with asthma."

But he added that: "More studies are needed to further examine the drug's impact."

Zangrilli, J. G. et al. Predose and Postdose Forced Expiratory Flow Between 25 per cent and 75 per cent in Adolescents and Adults With Asthma Treated With Twice-Daily Budesonide/Formoterol Pressurized Metered-Dose Inhaler (BUD/FM pMDI) or BUD pMDI for 1 Year. Presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting held in Washington, USA, on March 16, 2009.

Pearlman, D.S. et al. Predose Forced Expiratory Flow Between 25 per cent and 75 per cent in Inhaled Corticosteroid (ICS) - Dependent Patients With Mild to Moderate or Moderate to Severe Persistent Asthma Receiving Budesonide/Formoterol Pressurized Metered-Dose Inhaler (BUD/FM pMDI). Presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting held in Washington, USA, on March 16, 2009.

Tags: Allergies & Asthma | North America | Child Health

Printer friendly page Printer friendly page