SIGN UP FOR UPDATES!
Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
ENGLEMED
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BOOKS AND GIFTS THIS WAY!
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here
SEARCH THIS SITE
Google

WWW Englemed
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
FreeDigitalPhotos
www.freedigitalphotos.net
FreeWebPhotos
www.freewebphoto.com
FROM OUR NEWS FEEDS
Lockdown leads to double unplanned pregnancies
Fri October 22nd - Unplanned pregnancies almost doubled during the first lockdown in the UK, a major study reports today. More
Promising development in treatment for glioblastoma multiforme
Fri October 22nd - A major advance in brain tumour research could pave the way for personalised treatment for the most deadly form of the disease, British scientists say. More
RECENT COMMENTS
On 09/10/2020 William Haworth wrote:
How long is recovery time after proceedure... on Ablation cuts atrial fibrillat...
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote:
https://epidemicj17.imascientist.org.uk/2017/06/21... on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...
OUR CLIENTS
THIS WEEK'S STORIES
ENGLEMED HEALTH NEWS - 19/1/09

Heart gene affects one per cent

Monday January 19th, 2009

As many as one per cent of the world's population carry a newly-discovered heart disease gene, it was announced last night.

"Most" of these originate from the Indian sub-continent, where it affects all religions, castes and languages and in total four per cent of the population, researchers have reported.

People who carry the gene mutation, known as MYBPC3, have a "staggeringly" high risk of developing serious heart disease after middle age, according to the report in Nature Genetics.

Scientists first identified the gene five years ago when it was identified in two Indian families with the heart condition cardiomyopathy.

Research sponsors the Wellcome Trust describe the finding as of "great importance", enabling carriers to take steps to prevent the development of disease.

Researcher Perundurai S. Dhandapany, of Madurai Kamaraj University, Madurai, India, said: "The bad news is that many of these mutation carriers have no warning that they are in danger but the good news is that we now know the impact of this mutation."

Chris Tyler-Smith, from The Wellcome Trust Sanger Institute, Hinxton, UK, said: "We think that the mutation arose around 30,000 years ago in India, and has been able to spread because its effects usually develop only after people have had their children. A case of chance genetic drift: simply terribly bad luck for the carriers."

Researcher Kumarasamy Thangaraj, from the Centre for Cellular and Molecular Biology, Hyderabad, India, explained: "The mutation leads to the formation of an abnormal protein. Young people can degrade the abnormal protein and remain healthy, but as they get older it builds up and eventually results in the symptoms we see."

Dhandapany PS et al. (2008) A common Cardiac Myosin Binding Protein C variant associated with cardiomyopathies in South Asia. Nature Genetics Published online before print as doi: 10.1038/ng.309

Tags: Asia | Genetics | Heart Health | UK News | World Health

Printer friendly page Printer friendly page

CATEGORIES