Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here

WWW Englemed
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
Mitochondria mutations that may combat cancer
Fri April 9th - Mitochondrial DNA mutations found in cancer tumours are linked to improved chances of survival, researchers have found. More
Sun but not vitamin D may reduce COVID risk
Fri April 9th - Exposure to sun may have helped reduce mortality from COVID-19 – but vitamin D is probably not the explanation, according to a new UK study published today. More
On 09/10/2020 William Haworth wrote:
How long is recovery time after proceedure... on Ablation cuts atrial fibrillat...
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote: on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...
Clearing the air: An Assessment of Asthma and Indoor Allergens ABC of Asthma For more books click here
RSS graphic XML Graphic

Pre-birth bacteria exposure may prevent allergies

Wednesday December 9th, 2009

It's been thought for a long time that child-hood exposure to bacteria reduces the risk of asthma and allergy - but new findings suggest this begins in the womb.

The bacteria that pregnant women encounter may affect their child's risk of allergies, according to a new study.

Exposure to bacteria during pregnancy could trigger a reaction which protects the unborn child, say Dr Melanie Conrad and her team at Philipps-University of Marburg in Germany.

It is widely thought that young children's exposure to bacteria may cause their immune system to tolerate allergens later in life. But the researchers believe this process may begin during pregnancy.

They exposed pregnant mice to bacteria from a barn-yard. Their babies were born resistant to asthma symptoms like allergies of the airways.

This was probably due to the bacteria causing mild inflammation, increasing proteins called "Toll-like receptors", and dampening down the immune system.

The experts aren't sure how Toll-like receptors are linked to allergy resistance in offspring, only that they "play a pivotal role". They also don't know whether the protection applies to a broad range of allergens, including foods.

Details are published in the Journal of Experimental Medicine.

Dr Conrad writes that the experiment shows a "direct relationship" between bacterial exposure during pregnancy and asthma protection in the child. It could lead to better ways of preventing asthma, she hopes.

Child health expert Dr Patrick Holt of the University of Western Australia, says there is now good evidence that allergy protection can "occur in the developing foetus as a result of microbial stimulation of the pregnant mother".

He also predicts that this mechanism, if confirmed, could apply to many other diseases.

Conrad, M. L. et al. Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbe Acinetobacter lwoffii F78. The Journal of Experimental Medicine, published online December 7, 2008.

Holt, P. G. and Strickland, D. H. Soothing signals: transplacental transmission of resistance to asthma and allergy. The Journal of Experimental Medicine, published online December 7, 2008.

Tags: Allergies & Asthma | Child Health | Childbirth and Pregnancy | Europe | Women’s Health & Gynaecology

Printer friendly page Printer friendly page