Sign up for Englemed updates from TwitterSign up for Englemed updates from Facebook
Contact Englemed
Our contact email address.
We can provide a specialist, tailored health and medical news service for your site.
Click here for more information
RSS graphic XML Graphic Add to Google
About Englemed news services - services and policies.
Englemed News Blog - Ten years and counting.
Diary of a reluctant allergy sufferer - How the British National Health Service deals with allergy.
BookshopFor books on women's health, healthy eating ideas, mental health issues, diabetes, etc click here

WWW Englemed
Copyright Notice. All reports, text and layout copyright Englemed Ltd, 52 Perry Avenue, Birmingham UK B42 2NE. Co Registered in England No 7053778 Some photos copyright Englemed Ltd, others may be used with permission of copyright owners.
Disclaimer: Englemed is a news service and does not provide health advice. Advice should be taken from a medical professional or appropriate health professional about any course of treatment or therapy.
Heart failure linked to heavy energy drink consumption
Fri April 16th - Drinking excessive energy drinks could be linked to a young man’s heart failure, according to doctors who treated a 21-year-old who consumed four cans a day for two years. More
Shift workers' heart health linked to body clock
Fri April 16th - The risk of heart disease becomes greater the more an individual works outside of their natural body clock, new research suggests. More
Infection much greater risk than vaccines for thrombotic events
Fri April 16th - Cerebral venous thrombosis has been a significant complication of COVID-19 at a rate far higher than seen after vaccination, British researchers have reported. More
On 09/10/2020 William Haworth wrote:
How long is recovery time after proceedure... on Ablation cuts atrial fibrillat...
On 08/02/2018 David Kelly wrote:
Would you like to write a piece about this to be i... on Researchers unveil new pain re...
On 23/10/2017 Cristina Pereira wrote: on HIV breakthrough - MRC...
On 12/09/2017 Aparna srikantam wrote:
Brilliant finding! indeed a break through in under... on Leprosy research breakthrough...
On 01/07/2017 Annetta wrote:
I have been diagnosed with COPD for over 12 years.... on Seaweed plan for antimicrobial...

Genes explain why first-born babies are more allergic

Wednesday May 21st, 2008

First-born children face an increased risk of developing asthma and allergy, according to a study of British children.

The research suggests that first-borns experience different conditions in the womb from their later siblings.

The team collected information on more than 1,200 newborns in the Isle of Wight, UK.

They tested the children's genes, and found that they often had a form of the gene called IL-13 which is linked to increased IgE in the blood.

Higher levels of IgE - an antibody - indicate an increased allergic response. When the children were tested at ages four and ten, they were more likely to have allergies than children who were not the first-born.

Researcher Dr Wilfried Karmaus of the University of South Carolina, USA, said: "This is the first study to test whether the effect of genes involved in the development of asthma and allergy differs between first- and later-born children.

"We were not surprised that birth order had an effect on the development of the immune system, but were surprised that this interaction persisted at least to age ten. Our findings add to the evidence that allergic reactions are programmed during pregnancy and then affect the disease in later life."

This could explain the increasing rates of asthma and allergies in children in the last 30 years, because of the falling birth rate, he added. It could also lead to "new and exciting avenues of intervention".

The findings will be presented today (May 21) at the American Thoracic Society's 2008 International Conference in Toronto, Canada.

Research presented at the American Thoracic Society International Conference, held in Toronto, Canada from May 16-21, 2008.

Books on Asthma and Allergy Care

Tags: Allergies & Asthma

Printer friendly page Printer friendly page